The National Investor

In one of a couple currently discussed stories of ours we've been patient with, appearances are growing that GT Biopharma is "coming back from the dead."

As C.E.O. Breen explains, GT Biopharma is on a quest to improve cancer care and come up with modern remedies for an industry that is still relying on much the same "barbaric" regimens (essentially, "cut and burn") employed for some 80 years now. As we discuss, its platform technology suggests, together with some early clinical success, that the company has the goods!

Further, it now has sufficient backing from a couple key investors to continue with key clinical trials for the foreseeable future on its patented immunotherapy platform for the treatment of cancer, developed by world renown scientist Dr. Jeffrey Miller from the Univ. of Minnesota.

As I've stressed with other speculative stories recently -- both in advising our Members to leave some for a while and also embrace a few new "fresh" stories -- GT Biopharma has great potential to move the needle (and its sub-$10 million market cap presently) within MONTHS as opposed to years.

Do your due diligence here...I'm confident you'll come away as excited about this risk-reward setup as is possible with pretty much ANY kind of company!

Here, Exploits' CEO Jeff Swinoga joins me to give an overview of this newest exploration junior to my recommended list. As he explains, Exploits is essentially a "new" company now, focused on uber-attractive exploration projects acquired in recent months in both Quebec and Ontario.

Just closing on the sale of its Newfoundland assets as we're posting this, Exploits now is in great shape financially going into 2026.

MORE IMPORTANT, as you'll hear, we have the potential here for some very near-term news that would move the needle!

Jeff gives you a look at these two areas, which will be led initially by exploration in Quebec.

Moving on, I ask about Jeff's observations of the broader mining industry, government policy and the like in Canada; not only as a CEO and involved in other companies over time, but as a Board Member of P.D.A.C.

TO LEARN MORE, visit Exploits at https://www.exploitsdiscovery.com/

Ahead of a packed agenda at the Resourcing Tomorrow Conference in London, C.E.O. Ross Orr and I visit to discuss the heightened interest in the company's patent application filing of earlier this year and the breakthrough technology behind it.

This "Zero Waste" process that can take BILLIONS of tons of mining waste the world over (starting, first, with BacTech targeting old tailings in Canada's Sudbury Basin) could provide massive benefits to the environment while unlocking myriad products--even fertilizer!--as a part of the process of completely elinminating old tailings/waste.

We go on to discuss the pending(?) Tenguel Project in Ecuador and its off-the-charts economics...all awaiting the right financing deal...and we muse beyond that on the vast upside STILL in Ecuador, together with present success stories.

CHECK OUT BacTech's revamped website at https://bactechgreen.com/

Here I visit with Victor once again in the wake of the Monday, Dec. 1 news that Amex has again dramatically increased the size of its holdings in the Abitibi...from under 200 sq. km. to 500 sq. km!

Victor explains the whys and wherefores of this...and the work now started on the Feasibility Study for the "starter" mine at Perron.

As you'll hear anew, the economics of this initial project are off the charts! Indeed, toward the end of our discussion Victor explains how gold could go all the way back to $2,000/ounce...and Perron would STILL be an elite project!!

Along the way, we muse, too, over the gold bull market: together with investors finally waking up to just how strong Amex's story is, we've seen nearly a FIVE-FOLD run in its share price from the low earlier this year.

LINKS:

Our discussion from September, detailing the updated PEA on the Perron Project, now going toward a Feasibility Study: https://www.youtube.com/watch?v=_7VgU16S0ac

Amex's website: https://www.amexexploration.com/

Here, Chris is joined by Executive Director Mark Compton and Projects Manager Devon Coquillard to discuss the upcoming annual meeting (the 131st!!) of the A.E.M.A. to be held in the Reno, Nevada area.

This venerable organization is part trade group, part public advocate and always an incubator for everything to do with mining and ancillary industries. As you'll learn in this overview, the upcoming conference will be LOADED with technical knowledge, new technologies, job opportunities (in some of the highest paying sectors in America) and MUCH more.

As you may well already know from our own coverage of these industries, public policy and more, extractive industries and associated ones overall are enjoying their biggest renaissance in many years; this, of course, as economic and national security imperatives are driving this trend. Opportunities abound; and yet so, too, do the still-daunting tasks ahead of us which will require much more in the way of a national industrial, energy and economic policy--with the proper investments--to succeed.

For more on the A.E.M.A., visit https://www.miningamerica.org/

To learn specifically about the annual meeting agenda, see https://www.miningamerica.org/annualmeeting

(NOTE: As Devon indicates in our discussion, though on-line pre-registrations have closed, you can STILL register on site.)

Here I catch up anew with Des O'Kell of Enterprise Group.

This company's shares were a 10-bagger for us not all that long ago; since then, renewed bearish sentiment even in Canada's compelling energy patch has cut E shares by more than half from their last major high; as I argue herein, a great point to load up anew!

Des and I cover some of the company's news and key transactions of recent months for nearly the first half of this discussion.

We then go on to our always-provocative macro and public policy decisions concerning energy in both the U.S. and (mostly, of course!) Canada...

Our conclusion is that the Carney government -- for its other many faults -- is clearly of a mind to boost Canada's natural gas production and exports.

And in that sense, we opine on the compelling opportunity for investors, especially those focusing on the best stories in Western Canada's sedimentary basin. Unlike in The U.S.'s key shale areas--which, as Des sees it, are "in the Top of the Eighth inning"--in Canada it's more like the Top of the Third inning.

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LINKS:

-- Des and Stu's most recent "Pragmatics" podcast, including deeper dives into Canadian policy under Carney and other news affecting investors: https://desokell.podbean.com/

-- More background on Enterprise Group can be gleaned from its web site at https://enterprisegrp.ca/

-- My mid-year operational/company wrap up with Des: https://www.youtube.com/watch?v=rb8drGZi24c

Here, I'm joined once more by Dennis Calvert, CEO of BioLargo (OTCQX-BLGO who also serves as Chairman of subsidiary company Clyra Medical

Also joining us is Clyra's C.E.O. Steve Harrison, who has collaborated with Dennis for some 30 years now; and in this instance, with the fruits of their labors seemingly in reach!

Specifically, the company announced on November 13 its partner to handle initial sales of ViaClyr, likely to commence in early 2026. This will be the first of a series of wound care, surgical, dental and other products developed with Clyra's breakthrough technologies.

AND as you'll be learning -- or learning anew as the case may be -- Clyra Medical's wares represent legitimate BREAKTHROUGH science and better treatments!

To learn more visit BioLargo's "Master" web site at https://www.biolargo.com/

Clyra Medical's site specifically is at https://www.clyramedical.com/

As I've discussed it previously and recap here, Arizona Gold & Silver's Philadelphia Project in western Arizona is one of the more unique geological stories I've ever encountered. And as the time since my coverage has started has gone on, the company--led on the ground by V.P. of Exploration Greg Hahn--has incrementally been proving their thesis: that around and underneath a "dome" cover here, there is a multi-million ounce gold resource waiting to be found.!

C.E.O. Mike Stark wraps up some of the more recent news, including step-out drilling and a VERY successful metallurgy test on some test ores, both of which lend credence to the likelihood of a major resource here, if not a renewed district play in the Oatman District.

And we wrap up with some recent news from AZS' Silverton Project in eastern Nevada: a prospective (but essentially "greenfield") gold project with enough antimony uncovered in recent trenching to add this to the exploration mix for 2026.

LINKS:

-- Background on the Philadelphia Project, its geology, etc. via an earlier video interview with Greg Hahn: https://www.youtube.com/watch?v=A4kKzk3XrTM

-- Arizona Gold and Silver's web site is at https://arizonagoldsilver.com/
(make sure to look around at the various media, etc. linked here that Mike mentions!)

With red-hot Alaska more on the minds of the markets thanks to the Trump Administration, it's timely for us to get an update here from Tony Reda!

Tectonic has one of THE juiciest gold exploration stories anywhere in the U.S. That it's in Alaska--and has such high-profile backing as you'll learn here anew--makes it all the more attractive.

Tony runs us through recent news concerning Alaska as well as Tectonic's progress toward its Maiden Mineral Resource Estimate planned for 2026.

This is one of the relatively "cleanest" exploration stories out there; yet one with some of the wildest potential discovery upside you'll find as well.

So, especially now with an overdue (and healthy) correction in PM stocks underway, it's especially time to do your homework here...and then place your bets!

LINKS:

Tectonic's web site: https://www.tectonicmetals.com/

My initial video profile of Tectonic, valuable for a LOT of foundational information on the company's relationship with Doyon--the Alaska Native corporation that's TECT's 2nd largest shareholder--as well as background on the property's specific characteristics/attractiveness: https://www.youtube.com/watch?v=D97n4PJYWJ4